Down syndrome

noun

variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

called also trisomy 21

Examples of Down syndrome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
There are both physical and developmental symptoms of Down syndrome. Angelica Stabile, Fox News, 7 Oct. 2024 For instance, a requirement that children must be potty trained by age three can be unattainable for some children with Down syndrome or autism. Rachelle Rutherford, Forbes, 29 Oct. 2024 This year's photo series features 62 individuals with Down syndrome ages 1 to 36. Anna Lazarus Caplan, People.com, 22 Oct. 2024 As a guest on the Wednesday, Oct. 16 episode of the Club Shay Shay podcast hosted by Shannon Sharpe, the rapper, 54, claimed that his ex abandoned him and their son Joey, now 33, after their son was diagnosed with Down syndrome at birth. Emma Aerin Becker, People.com, 17 Oct. 2024 See all Example Sentences for Down syndrome 

Word History

Etymology

J. L. H. Down †1896 English physician

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of Down syndrome was in 1961

Dictionary Entries Near Down syndrome

Cite this Entry

“Down syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Down%20syndrome. Accessed 1 Dec. 2024.

Kids Definition

Down syndrome

noun
ˈdau̇n-
variants or Down's syndrome
ˈdau̇n(z)-
: a genetic condition characterized especially by developmental delays, by distinctive physical traits (as short stature and upward slanting eyes), and by the presence of three chromosomes numbered 21 in human beings
Etymology

named for J.L.H. Down, 1828–1896, English doctor

Medical Definition

Down syndrome

noun
variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, relatively small head, upward slanting eyes usually with epicanthal folds, flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

called also Down, Down's, trisomy 21

More from Merriam-Webster on Down syndrome

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